Background: The appropriate communication among the doctor and the patient is a highly necessary element of the treatment procedure. This is the reason doctors should develop some essential communication skills. Empathy is one of them, which is the ability to express true interest that can be perceived. Empathy may be inherent or can be taught. Empathy has been scientifically proved that it provides both patient and doctor numerous benefits. Researchers have created various measuring tools to evaluate empathy. Aim: The present study was conducted to evaluate doctor's empathy in the region of Evia. Evia is an island with rural and semi-urban population, facing lack of medical personnel. Methodology: An anonymous questionnaire used to collect data. The questionnaire included various questions related to population statistics and the Jefferson Scale of Patients’ Perceptions of Physician Empathy (JSPPPE). The adults participated in the research were 201, all of them living permanently in the Island of Evia. Results: The statistical analysis of the association between the population statistics and the results of the Jefferson Scale, indicated that the doctor’s employment status (p˂0.001), patient’s profession (p=0.0017), income (p=0.001) and type of health insurance (p=0.004) are related to the way doctor’s empathy is perceived by the patient. Conclusions: The statistical analysis that resulted from the association of the population statistics with the Jefferson Scale scores, indicates that doctors in Evia show relatively satisfying levels of empathy. It is proved that patients’ occupation, income and health insurance effect the way empathy is perceived. Empathy perception is also effected by doctors’ professional status. The high scores achieved by doctors working in the private sector should provoke some concerns regarding the quality of the public health services and lead to further research.