DC FieldValueLanguage
dc.contributor.authorTerentes-Printzios, Dimitrios-
dc.contributor.authorDima, Ioanna-
dc.contributor.authorBenardos, Panorios-
dc.contributor.authorMitrou, Panagiota-
dc.contributor.authorMathioudakis, Konstantinos-
dc.contributor.authorTsolakidis, Anastasios-
dc.contributor.authorBarkas, Fotios-
dc.contributor.authorTsioufis, Konstantinos-
dc.contributor.authorSfikakis, Petros P.-
dc.contributor.authorLiberopoulos, Evangelos-
dc.contributor.authorVlachopoulos, Charalambos-
dc.date.accessioned2025-03-07T14:51:39Z-
dc.date.available2025-03-07T14:51:39Z-
dc.date.issued2024-06-01-
dc.identifierscopus-85189921526-
dc.identifier.issn2772-4875-
dc.identifier.other85189921526-
dc.identifier.urihttps://uniwacris.uniwa.gr/handle/3000/3009-
dc.description.abstractBackground: Despite recent guidelines appropriate lipid-lowering treatment (LLT) remains suboptimal in everyday clinical practice. Aims: We aimed to describe clinical practice of use of LLT for at least high CV risk populations in a Hellenic real-world setting and assess how this relates to the European Society of Cardiology treatment guidelines. Methods: We analyzed data from a retrospective cohort study of the National Registry of patients with dyslipidemia between 1/7/2017 and 30/6/2019 who were at least of high CV risk and filled a dual or triple lipid-lowering treatment (dLLT, tLLT) prescription. The primary outcomes of interest of this analysis were to report on the patterns of LLT use in at least high CV risk patients. Results: A total of 994,255 (45.4% of Greeks on LLT) were of at least high CV risk and 120,490 (5.5%) were on dLLT or tLLT. The percentage of patients with reported statin intolerance ranged from 2 to 10%. While persistence was reported to be satisfactory (>85% for both dLLT or tLLT), adherence was low (ranging between 14 and 34% for dLLT). In 6-month intervals, the percentage of patients achieving a low-density lipoprotein cholesterol (LDL-C) target below 100 md/dL ranged from 20% to 23% for dLLT and 34%–37% for tLLT. Conclusions: The prevalence of at least high CV risk patients among patients receiving LLT in Greece is substantial. Despite the high persistence and probably due to the low adherence to treatment, LDL-C remains above targets in more than two thirds of patients.en_US
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Cardiology. Cardiovascular Risk and Preventionen_US
dc.subjectCardiovascular risken_US
dc.subjectDyslipidemiaen_US
dc.subjectEzetimibeen_US
dc.subjectFamilial hypercholesterolaemiaen_US
dc.subjectLDL-Cholesterolen_US
dc.subjectLipid-lowering therapy’ statinsen_US
dc.subjectPCSK9 inhibitorsen_US
dc.titleReal-world data on treatment patterns in at least high cardiovascular risk patients on dual and triple lipid lowering therapy in a Hellenic nationwide e-prescription databaseen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.ijcrp.2024.200261en_US
dc.identifier.scopus2-s2.0-85189921526-
dcterms.accessRights1en_US
dc.relation.deptDepartment of Archival, Library and Information Studiesen_US
dc.relation.facultySchool of Administrative, Economics and Social Sciencesen_US
dc.relation.volume21en_US
dc.collaborationUniversity of West Attica (UNIWA)en_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.journalsOpen Accessen_US
dc.publicationPeer Revieweden_US
dc.countryGreeceen_US
local.metadatastatusverifieden_US
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
crisitem.author.deptDepartment of Archival, Library and Information Studies-
crisitem.author.facultySchool of Administrative, Economics and Social Sciences-
crisitem.author.orcid0000-0001-7364-4542-
crisitem.author.parentorgSchool of Administrative, Economics and Social Sciences-
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