DC FieldValueLanguage
dc.contributor.authorBournia, Vasiliki-Kalliopi-
dc.contributor.authorFragoulis, George E.-
dc.contributor.authorMitrou, Panagiota-
dc.contributor.authorMathioudakis, Konstantinos-
dc.contributor.authorTsolakidis, Anastasios-
dc.contributor.authorKonstantonis, George-
dc.contributor.authorTseti, Ioulia-
dc.contributor.authorVourli, Georgia-
dc.contributor.authorTektonidou, Maria G.-
dc.contributor.authorParaskevis, Dimitrios-
dc.contributor.authorSfikakis, Petros P.-
dc.date.accessioned2025-03-09T19:02:02Z-
dc.date.available2025-03-09T19:02:02Z-
dc.date.issued2023-03-01-
dc.identifierscopus-85149172022-
dc.identifier.issn1462-0332-
dc.identifier.issn1462-0324-
dc.identifier.other85149172022-
dc.identifier.urihttps://uniwacris.uniwa.gr/handle/3000/3029-
dc.description.abstractObjectives: To investigate coronavirus disease 2019 (COVID-19)-associated risk of hospitalization and death in RA, AS, PsA, SLE and SSc in comparison with the general population during the first year of the pandemic, and compare their overall mortality with 2019. Methods: Interlinking nationwide electronic registries, we recorded confirmed COVID-19-associated infections, hospitalizations and deaths, and all-cause deaths between 1 March 2020 and 28 February 2021 in all adults with RA, AS, PsA, SLE and SSc under treatment (n = 74 970, median age 67.5, 51.2, 58.1, 56.2 and 62.2 years, respectively) and in random comparators from the general population matched (1:5) on age, sex and region of domicile. Deaths from all causes during 2019 were also recorded. Results: Compared with the general population, incidence rates (IR) for COVID-19-associated hospitalization were higher in RA [IR ratio (IRR) 1.71(1.50-1.95)], SLE [2.0 (1.4-2.7)] and SSc [2.28 (1.29-3.90)], while COVID-19-associated death rates were higher in RA [1.91 (1.46-2.49)]. When focusing only on severe acute respiratory syndrome coronavirus 2-infected subjects, after adjusting for age and gender, the odds ratio for COVID-19 associated death was higher in RA [1.47 (1.11-1.94)] and SSc [2.92 (1.07-7.99)] compared with the general population. The all-cause mortality rate compared with the general population increased in RA during the first year of the pandemic (IRR 0.71) with reference to 2019 (0.59), and decreased in SSc (IRR 1.94 vs 4.36). Conclusion: COVID-19 may have a more severe impact in patients with systemic rheumatic disease than in the general population. COVID-19-related mortality is increased in subgroups of patients with specific rheumatic diseases, underscoring the need for priority vaccination and access to targeted treatments.en_US
dc.language.isoenen_US
dc.relation.ispartofRheumatologyen_US
dc.subjectASen_US
dc.subjectCOVID-19en_US
dc.subjectPsAen_US
dc.subjectRAen_US
dc.subjectSLEen_US
dc.subjectSScen_US
dc.titleDifferent COVID-19 outcomes among systemic rheumatic diseases: a nation-wide cohort studyen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/rheumatology/keac422en_US
dc.identifier.scopus2-s2.0-85149172022-
dcterms.accessRights1en_US
dc.relation.deptDepartment of Archival, Library and Information Studiesen_US
dc.relation.facultySchool of Administrative, Economics and Social Sciencesen_US
dc.relation.volume62en_US
dc.relation.issue3en_US
dc.identifier.spage1047en_US
dc.identifier.epage1056en_US
dc.collaborationUniversity of West Attica (UNIWA)en_US
dc.subject.fieldMedical and Health Sciencesen_US
dc.journalsOpen Accessen_US
dc.publicationPeer Revieweden_US
dc.countryGreeceen_US
local.metadatastatusverifieden_US
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
crisitem.author.deptDepartment of Archival, Library and Information Studies-
crisitem.author.facultySchool of Administrative, Economics and Social Sciences-
crisitem.author.orcid0000-0001-7364-4542-
crisitem.author.parentorgSchool of Administrative, Economics and Social Sciences-
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