Corporate Social Responsibility (CSR) and Sustainable Development (SD) are the means through which the development of man and society is achieved. Social Enterprises (SEs) belong to the field of economy, which ensures the proper functioning of a society, mitigating injustices and enhancing justice and equality. Based on these, highlighting the way through which SD can relate to CSR and SEs in the health sector is vital. In comparison with the European Union countries, social entrepreneurship is not that developed in Greece. SEs in the Greek health sector are fewer than in other fields with most of them concerning the provision of mental health services, as well as managing the problems faced by the elderly and disabled population. However, there are examples aiming at SD through actions that promote green and social public contracts, waste management and the cooperation between hospitals and SEs. The health sector can benefit from SEs provided that they cooperate through CSR and SD strategies and policies, which would be supported and promoted by the state itself.