The entrance of Social Media in everyday life has changed the way people communicate with each other. This has affected all areas and the daily routine of people. This dynamic entrance of Social Media also affects the field of health, one of the most important areas of people's lives. Doctors and Dentists throughout Greece are approximately 78,760 according to the Hellenic Statistical Authority data for 2017. The competition in this field is very high and medical marketing has become an indispensable tool for all health professionals. This study focuses on the Doctor-patient relationship in the era of the continuously use of Social Media. This Paper highlights matters arising both ways, from the patient's side but also from the perspective of a Doctor.