Disadvantaged families living in poverty, especially those living in deprived neighborhoods where risks tend to accumulate, have diverse needs for support. Throughout Europe different models of service-coordination and integration exist, but a systematic overview of experiences and evidence on effectiveness is not available. The aim of this initial review is to: - identify facilitators and challenges at the interpersonal and at the structural-organizational level that are relevant to successful coordination, collaboration and integration of multiple services for young children (e.g. communication, case management, financial resources, policy measures); - identify models of working and domains for the development of a common framework; - summarize the potential impact of inter-agency working upon children, families and communities.