This chapter analyzes the importance of organizational culture through a set of strategies and enterprising practices in order to emphasize the culture’s necessity for the effective management of any organization and especially for the management of telecommunication companies. Moreover, the way culture affects the success and failure of a series of enterprising practices, such as mergers, acquisitions, strategic alliances and joint ventures is presented. All these create a rather interesting framework in which organizational managers should cultivate and implement the appropriate organizational culture in order to keep their organization competitive and well managed. Finally, case studies from the telecommunications industry will be presented, a field where culture plays a dominant role in either changing procedure or in developing new enterprising practices.