The subject of this study pertains to issues emerging from archival research on private libraries from the 16th-century Venice. In essence, this means that we are going to deal with the ways in which combined research in bigger and smaller, more particu-lar archives of a specific nature, can enrich our knowledge concerning a number of questions about the private libraries’ contents: manuscripts and printed books. The key questions relate to the production of codices and relevant issues such as scribes’ identities and to matters concerning the circulation of printed books. We concentrate particularly on the private libraries of Greeks in Venice and on Greek manuscripts; moreover, on individual scribes who had settled in the Greek Community or who simply lived for a short period of time in the full of opportunities capital city of La Serenissima.We are going to focus upon two archival institutions established in the city of Venice, based on the present author’s experience of working for several years in them. The first is the Archive of the Hellenic Institute of Byzantine and Post-Byzantine Studies of Venice and the second, the well-known State Archives of Venice (Archivio di Stato di Venezia).Nevertheless, it should be noted that archival research in Venice can be also carried out in a multitude of archival institutions such as the Archive of the Library of the Correr Museum (Biblioteca del Museo Correr) and the Archive of the Querini Stampalia Library (Biblioteca della Fondazione Querini Stampalia), the Curia Patri-arcale Historical Archives (Archivio Storico del Patriarcato di Venezia); also, at the existing archives of the church institutions of the city as well as in the Manuscripts Department of the Marciana National Library (Biblioteca Nazionale Marciana,Dipar-timento Manoscritti e Rari).