The relation between Information and Computer sciences was always interactive. The exponential growth of the information and communication technologies during the last decades was exploited by the information/memory organizations to develop reliable and useful information services and disseminate easily and user-friendly information to all over the world. This evolution empowered the relations of both scientific communities, which produce in common research results and recently decided to establish or merge computer and information science schools. This paper presents the activities of the Digital Library and Electronic Publishing Laboratory of the Department of Archive and Library Sciences, Ionian University, Greece and describes instances form the collaboration of computer and information scientists employed by a variety of organizations such as Libraries, Archives and Records Management services, Museums, etc. The development of powerful large-scale systems and services makes evident that the interaction of the laboratory with the Greek information science community is creative and fruitful.