Enterprises today are facing intense pressures because of the increased competition, aiming at their survival. The purpose of this study is to investigate the factors that are derived from the relationship that is developed between supervisors and subordinates and finally leads to job satisfaction and high employee performance. The survey was conducted in private and public obstetric clinics in Greece through a sample of 100 subordinates and 30 supervisors, using a structured questionnaire with five-point Likert scale. The research results show that the main factor that affects job satisfaction and employee performance is the relationship that is developed between the supervisor and subordinate.