The development of Big Data Analytics (BDA) technology and the maturity of the Machine Learning (ML) sector offer great opportunities for applications in Intensive Care Units (ICUs). This paper describes a Conceptual Framework and proposes its use in designing architectures and big data applications in ICUs. The Conceptual Framework is based on BDA,MLNatural Language Processing (NLP) and consists of the following subsystems: The "Big Data Integration and ICUs"module, the "ICUs and critical care services"module, the "Use of standards and ICUs"module, the "Machine Learning and ICUs"module, and the "NLP and ICUs"module. The framework is developed using Soft System Methodology (SSM) and Design Science Research Methodology (DSRM).